Although we can limit the spread of HIV through the use of PreP medications, and protect the health of those already infected through antiretrovirals, the ability to cure HIV infection evades us. A new study has shown that an antibody called 10-1074 is effective at neutralizing the virus, and is also safe for human use. The successful trial means we’re one step closer in the long journey toward a cure.
The study, now published online in the journal Nature Medicine, details trials of the new HIV-neutralizing antibody in HIV-positive patients. According to the results, the antibody also led to high antiviral activity in these patients.
“These antibodies are highly potent and are able to effectively neutralize a large number of different HIV strains. Therefore, they play an important role in the quest for and development of an HIV vaccine,” explained Dr. Florian Klein, one of the researchers involved in the study, in a recent statement.
HIV is a virus, and like all viruses, our immune system creates antibodies to fight it. These antibodies recognize a virus or bacteria as a foreign body, and call on the immune system to destroy it. Unfortunately, in the case of HIV, the virus is able to evade our immune system by hiding out, reproducing, and eventually, if left untreated, completely destroying our immune system. Recent research into a cure and vaccine against HIV have focused on the use of specific antibodies that can better detect HIV.